International journal of conference series on education and social sciences (Online)

THE INFLUENCE OF HORMONAL STATUS ON SKIN CHRONOAGING PROCESSES: PATHOPHYSIOLOGICAL ASPECTS AND PREDICTIVE DIAGNOSTICS

2026-07-10T12:26:28+03:00

This paper presents a theoretical and practical analysis of the influence of
hormonal status on skin chronoaging processes. The study is based on an integrative approach
combining endocrinological assessment (estradiol, TSH, T4, prolactin) with high-frequency
ultrasound sonography (33 MHz and 75 MHz). Systemic hormonal imbalance is shown to
be a key predictor of dermal matrix degradation. The efficacy of a combined protocol
comprising microneedle RF lifting, thulium laser, and topical resveratrol therapy is
substantiated. The developed algorithm for personalized correction ensures a high degree of
treatment targeting, allowing involutional processes to be slowed and structural skin integrity
to be restored. These findings open new prospects for predictive anti-aging medicine and for
optimizing dermatocosmetology protocols based on evidence-based instrumental diagnostics.

ON THE WAY TO SUSTAINABLE DEVELOPMENT: THE REGIONAL IMAGE OF THE SOCIAL SECTOR

2026-06-16T02:19:28+03:00

This article analyzes regional aspects of sustainable social sector development,
socio-economic disparities between regions, and their impact on public welfare. The study
examines the regional characteristics of education, healthcare, social protection, and
infrastructure development, and substantiates the importance of a regional approach in
ensuring sustainable development. Additionally, scientific and practical recommendations
have been developed for the effective use of regional potential, the improvement of local
governance institutions, and the implementation of innovative mechanisms in the context of
Uzbekistan.

MULTIPARAMETRIC ASSESSMENT OF HEPATIC STEATOSIS IN NONALCOHOLIC FATTY LIVER DISEASE: AN INTEGRATED APPROACH USING TRANSIENT ELASTOGRAPHY, COMPUTED TOMOGRAPHY, AND MAGNETIC RESONANCE IMAGING

2026-06-25T18:29:50+03:00

Non-alcoholic fatty liver disease (NAFLD) is among the most prevalent chronic liver conditions
worldwide, affecting over 25% of the adult population according to WHO data. Accurate
quantification of hepatic steatosis remains a clinical challenge, as no single imaging modality
provides sufficient sensitivity and specificity across all degrees of fat accumulation.